102 Results for "

Salvia syriaca L.

" in MedChemExpress (MCE) Product Catalog:
Products (102)

102 Results for "Salvia syriaca L." in MCE Product Catalog:

47
Cryptotanshinone
Cryptotanshinone
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47 Publications Verification
Art. -Nr.: HY-N0174
CAS. Nr.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Category:  

Quinones Labiatae Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones Cancer

Target:  

STAT Autophagy

Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
36
Tanshinone IIA
Tanshinone IIA
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36 Cited Publications
Art. -Nr.: HY-N0135
CAS. Nr.: 568-72-9
Synonyms: Dan Shen ketone
Category:  

Quinones Labiatae Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants Disease Research Fields Naphthalene Quinones Cancer

Target:  

VEGFR

Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
20
Salvianolic acid B
Salvianolic acid B
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20 Cited Publications
Art. -Nr.: HY-N1362
CAS. Nr.: 121521-90-2
Synonyms: Lithospermic acid B
Category:  

Cardiovascular Disease Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields

Target:  

Autophagy

Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.
14
Dihydrotanshinone I
Dihydrotanshinone I
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14 Cited Publications
Art. -Nr.: HY-N0360
CAS. Nr.: 87205-99-0
Category:  

Cardiovascular Disease Quinones Labiatae Samanea saman (Jacq.) Merr. Plants Phenanthrenequinones Disease Research Fields

Target:  

SARS-CoV

Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.
7
Homoplantaginin
Homoplantaginin
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7 Cited Publications
Art. -Nr.: HY-N1949
CAS. Nr.: 17680-84-1
Category:  

Flavonoids Flavones Labiatae Cassia Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

TNF Receptor NF-κB

Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinflammatory and antioxidant properties. Homoplantaginin could inhibit TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
6
Lithospermic acid
Lithospermic acid
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6 Cited Publications
Art. -Nr.: HY-N0823
CAS. Nr.: 28831-65-4
Synonyms: (+)-Lithospermic acid
Category:  

Labiatae Samanea saman (Jacq.) Merr. Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

NO Synthase AMPK Keap1-Nrf2 Xanthine Oxidase Apoptosis

Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .
4
Danthron
Danthron
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4 Cited Publications
Art. -Nr.: HY-B0923
CAS. Nr.: 117-10-2
Synonyms: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
Category:  

Quinones Labiatae Anthraquinones Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

AMPK Autophagy Bacterial Virus Protease

Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
3
Sclareol
Sclareol
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3 Cited Publications
Art. -Nr.: HY-N0128
CAS. Nr.: 515-03-7
Category:  

Labiatae Terpenoids Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Cancer

Target:  

Environmental Pollutants Apoptosis

Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .
2
Miltirone
Miltirone
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2 Cited Publications
Art. -Nr.: HY-N1951
CAS. Nr.: 27210-57-7
Synonyms: Rosmariquinone
Category:  

Labiatae Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants

Target:  

GABA Receptor Apoptosis Carboxylesterase (CES) SARS-CoV

Miltirone is an orally active natural compound found in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC50 of 0.3 μM. Miltirone induces ROS - and-p53 dependent apoptosis. Miltirone inhibits carboxylesterase 2 (CES2; Ki = 0.04 μM) and SARS-CoV main protease (Mpro) .
1
Przewaquinone A
Przewaquinone A
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1 Cited Publications
Art. -Nr.: HY-N1551
CAS. Nr.: 76843-23-7
Category:  

Quinones Labiatae Diterpenoids Plants Naphthalene Quinones Vachellia nilotica (L.) P. J. H. Hurter & Mabb.

Target:  

Others

Przewaquinone A, a lipophilic diterpene quinone present only in Salvia przewalskii, induces a potent inhibitory action on vascular contraction .
1
Methyl carnosate
Methyl carnosate
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1 Cited Publications
Art. -Nr.: HY-136150
CAS. Nr.: 82684-06-8
Category:  

Infection Labiatae Terpenoids Samanea saman (Jacq.) Merr. Phenols Polyphenols Diterpenoids Plants Disease Research Fields

Target:  

Bacterial

Methyl camosate is a diterpene isolated from Salvia officinalis or Rosmarinus officinalis. Methyl camosate has potent antioxidant and anti-bacterial activity .
1
Bulnesol
Bulnesol
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1 Cited Publications
Art. -Nr.: HY-N10014
CAS. Nr.: 22451-73-6
Category:  

Cupressaceae Neocallitropsis pancheri Terpenoids Sesquiterpenes Plants

Target:  

Fungal

Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC50 value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .
Salvinorin A
Salvinorin A
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Art. -Nr.: HY-100845
CAS. Nr.: 83729-01-5
Synonyms: Divinorin A
Category:  

Labiatae Terpenoids Diterpenoids Plants Vachellia nilotica (L.) P. J. H. Hurter & Mabb.

Target:  

Opioid Receptor

Salvinorin A is a potent, unique and short-acting high efficacy kappa-opioid receptor (KOPr) agonist with Ki value of 4.3 nm. Salvinorin A is a non-nitrogenous neoclerodane isolated from Salvia divinorum.
Neocryptotanshinone
Neocryptotanshinone
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Art. -Nr.: HY-119720
CAS. Nr.: 109664-02-0
Reinheit:  98.82%
Category:  

Quinones Labiatae Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants Disease Research Fields Inflammation/Immunology Naphthalene Quinones

Target:  

NF-κB NO Synthase

Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways .
Neoprzewaquinone A
Neoprzewaquinone A
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Art. -Nr.: HY-N3201
CAS. Nr.: 630057-39-5
Category:  

Labiatae Terpenoids Samanea saman (Jacq.) Merr. Other Diseases Diterpenoids Plants Disease Research Fields

Target:  

Others

Neoprzewaquinone A is isolated from the roots of Salvia miltiorrhiza .
Manool
Manool
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Art. -Nr.: HY-N1039A
CAS. Nr.: 596-85-0
Category:  

Labiatae Terpenoids Diterpenoids Plants Pteris semipinnata L. Sp. Disease Research Fields Cancer Vachellia nilotica (L.) P. J. H. Hurter & Mabb.

Target:  

Others

Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle .
Tanshinone IIB
Tanshinone IIB
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Art. -Nr.: HY-N1179
CAS. Nr.: 17397-93-2
Category:  

Cardiovascular Disease Quinones Neurological Disease Labiatae Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones

Target:  

Apoptosis

Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis .
Tanshinone IIA anhydride
Tanshinone IIA anhydride
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Art. -Nr.: HY-N10686
CAS. Nr.: 61077-78-9
Category:  

Flavonoids Labiatae Samanea saman (Jacq.) Merr. Plants Other Flavonoids

Target:  

Carboxylesterase (CES)

Tanshinone IIA anhydride, present in root extracts of Salvia miltiorrhiza, acts as an inhibitor of human carboxylesterase (CE). Tanshinone IIA anhydride has a Ki value of 1.9 nM against hCE1 and a Ki value of 1.4 nM against hiCE. Tanshinone IIA anhydride forms a stable covalent complex with serine Ser221 at the active site of hCE1, blocking the catalytic cycle of carboxylesterase, and the activity of the inactivated enzyme cannot recover spontaneously. Tanshinone IIA anhydride is applicable in metabolism-related studies .
Tanshinlactone
Tanshinlactone
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Art. -Nr.: HY-N1180
CAS. Nr.: 105351-70-0
Category:  

Labiatae Terpenoids Samanea saman (Jacq.) Merr. Diterpenoids Plants

Target:  

SARS-CoV Keap1-Nrf2

Tanshinlactone is a compound found in Salvia miltiorrhiza with anti-coronavirus (CoV) and anti-tumor activities. Tanshinlactone induces methuocytic cell death (methuosis) by activating the NRF2 pathway, and selectively kills ER +, HER2 +/EGFR + breast cancer cells. Tanshinlactone is applicable to research related to breast cancer and coronavirus infections .
Trijuganone B
Trijuganone B
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Art. -Nr.: HY-N7761
CAS. Nr.: 126979-84-8
Synonyms: Tetrahydro tanshinone I
Target:  

Bacterial

Forschungsgebiete:  

Cancer

Trijuganone B (Tetrahydro tanshinone I) is a naturally occurring covalent pan-inhibitor of gut microbial bile salt hydrolases that can be isolated from Salvia trijuga. Trijuganone B inhibits total gut microbial bile salt hydrolase activity in live microorganisms and murine gut luminal content. Trijuganone B can be used for the research of bile-acid-related metabolic disorders .
Assay Types